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Technical Officer, Purification (Dowstream Process)

Priority may be given to the following designated employment equity groups: women, Indigenous peoples* (First Nations, Inuit and Métis) and persons with disabilities.
* The Employment Equity Act, which is under review, uses the terminology Aboriginal peoples and visible minorities.


City: Montréal 

Organizational Unit: Human Health Therapeutics 

Classification: TO-3 

Tenure: Term 

Duration: 2 years

Language Requirements: English or French 



There are two term positions to fill.

The NRC Advantage

Great Minds. One Goal. Canada's Success.


The National Research Council of Canada (NRC) is the Government of Canada's largest research organization supporting industrial innovation, the advancement of knowledge and technology development. We collaborate with over 70 colleges, universities and hospitals annually, work with 800 companies on their projects, and provide advice or funding to over 8000 Small and Medium-sized Enterprises (SMEs) each year.


We bring together the brightest minds to deliver tangible impacts on the lives of Canadians and people around the world. And now, we want to partner with you.  Let your expertise and inspirations make an impact by joining the NRC.


At the NRC, we know that diversity enables excellence in research and innovation. We are committed to a diverse and representative workforce, a safe and respectful work environment, and contributing to a more inclusive Canadian innovation system.  We welcome all qualified applicants and encourage you to complete the employment equity self-declaration questions during the job application process.

Please let us know of any accommodation measures required to help you to be assessed in a fair and equitable manner. Please note that the information you provide will be treated confidentially. 

Your Challenge

Help bring research to life and drive your career forward with the National Research Council of Canada (NRC), Canada’s largest research and technology organization.


We are looking for a Technical Officer in Purification to support GMP operations at our new Clinical Trial Material Facility with the Human Health and Therapeutics (HHT) Research Centre. The Technical Officer would be someone who shares our core values of Integrity, Excellence, Respect and Creativity.


The successful candidate will play an important role within a team in charge of the purification process of promising biotherapeutics and vaccines, from the technology transfer to the GMP manufacturing. The effort of this purification team will directly contribute to the clinical development of vaccines and therapeutic candidates for Canadian small and medium-sized enterprises (SME’s). Responsibilities of the candidate will include the provision of technical assistance in the preparation and the conduct of GMP productions, recording, and compiling scientific data, maintaining clean room and process equipment in a higly controlled  environment.  This technical officer position would appeal to someone who has a passion for working in a controlled laboratory (GMP) environment, providing their technical support to advance projects and contribute to establishing and improving standard operating procedures. You would demonstrate ability to take direction and follow established procedures, efficiently document result of technoclogical transfer and production activities and you enjoy performing laboratory and manufacturing work in a dynamic and fast-paced environment.

Screening Criteria

Applicants must demonstrate within the content of their application that they meet the following screening criteria in order to be given further consideration as candidates:


Bachelor in Sciences, Biotechnology, Engineering or related field. 

Collegial diploma combined with relevant and significant experience may be considered.


For information on certificates and diplomas issued abroad, please see Degree equivalency


  • Significant experience in the preparation and execution of technical tasks in a GMP laboratory environment of pharmaceutical or biotechnology production preferably related to vaccines and / or biotherapies (mandatory)
  • Significant experience with industrial purification process.
  • Significant experience in aseptic techniques and with single-use technology.
  • Significant experience in large scale solution preparation, tangential/dead-end filtration, large scale chromatography columns, virus inactivation/filtration, with automated production.

Each of the following is considered an important asset:

  • Experience working in biological containment level 2. 
  • Experience with large scale purification of monoclonal antibodies, fusion proteins.
  • Experience with large scale purification of viral vectors.

Condition of Employment

Reliability Status


Language Requirements

Assessment Criteria

Candidates will be assessed on the basis of the following criteria:

Technical Competencies

  • Good knowledge of GMP requirements applied to pharmaceutical or biopharmaceutical products
  • Ability to write and follow standard operating procedures (SOPs), to write controlled changes, to escalate and report any deviations and to write work instructions.
  • Working knowledge in aseptic techniques.
  • Working knowledge of in In-Process Testing related to purification process (e.g: pH/Conductivity, protein concentration by absorbance at 280 nm, measurement of endotoxins level)
  • Working knowledge in large scale purification process (filtration, chromatography, concentration/diafiltration, formulation)
  • Working knowledge in scaling-up purification process 
  • Ability to collaborate validation studies of manufacturing process and equipment qualification

Behavioural Competencies

  • Technology support - Teamwork (Level 2)
  • Technology support - Initiative (Level 2)
  • Technology support - Client focus (Level 2)
  • Technology support - Results orientation (Level 2)

Competency Profile(s)

For this position, the NRC will evaluate candidates using the following competency profile: Technology Support


View all competency profiles



Relocation assistance will be determined in accordance with the NRC's directives.


From $58,445 to $80,040 per annum. 



NRC employees enjoy a wide-range of competitive benefits including comprehensive health and dental plans, pension and insurance plans, vacation and other leave entitlements.


  • A pre-qualified list may be established for similar positions for a one year period.
  • Preference will be given to Canadian Citizens and Permanent Residents of Canada. Please include citizenship information in your application.
  • The incumbent must adhere to safe workplace practices at all times.
  • We thank all those who apply, however only those selected for further consideration will be contacted.



Please direct your questions, with the requisition number (12232) to:


Telephone: 343-548-5849 

Closing Date: 5 July 2022- 23:59 Eastern Time



For more information on career tools and other resources, check out Career tools and resources


*If you are currently a term or continuing employee at NRC, please apply through the SuccessFactors Careers module from your NRC computer.    Agente technique, Purification (Procédé en aval)


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