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Manufacturing Supervisor, Upstream

Priority may be given to the following designated employment equity groups: Women, Indigenous peoples* (First Nations, Inuit and Métis) and persons with disabilities*.
* The Employment Equity Act, which is under review, uses the terminology Aboriginal peoples. 


City: Montréal 

Organizational Unit: Biologics Manufacturing Centre 

Classification: RCO 

Tenure: Term 

Duration: Until March 31, 2023 with possibility for extension or permanent position under new business model.

Language Requirements: Bilingual Imperative BBB/BBB 


The NRC Advantage


The National Research Council of Canada (NRC) is the Government of Canada's largest research organization supporting industrial innovation, the advancement of knowledge and technology development. We collaborate with over 70 colleges, universities and hospitals annually, work with 800 companies on their projects, and provide advice or funding to over 8000 Small and Medium-sized Enterprises (SMEs) each year.

We bring together the brightest minds to deliver tangible impacts on the lives of Canadians and people around the world. And now, we want to partner with you.  Let your expertise and inspirations make an impact by joining the NRC.

At NRC, we know diversity enables excellence in research and innovation. We are committed to a diverse and representative workforce, an open and inclusive work environment, and contributing to a more inclusive Canadian innovation system. 

NRC welcomes all qualified applicants and encourages candidates to self-declare as members of the following designated employment equity groups: women, visible minorities, aboriginal peoples and persons with disabilities.

Please advise of any accommodation measures required to enable you to be assessed in a fair and equitable manner. They are available to all candidates for further assessment. Related information received will be addressed confidentially.

Your Challenge

Help bring research to life and drive your career forward with the National Research Council of Canada (NRC), Canada's largest research and technology organization.

We are looking for a Manufacturing Supervisor, Upstream, to support our Biologics Manufacturing Centre. The selected candidate would be someone who shares our core values of Integrity, Excellence, Respect and Creativity.

The new Biologics Manufacturing Centre (BMC), at NRC, will help to improve the health of and makes biomedical innovations more accessible to all Canadians by providing access to additional domestic production capacity for vaccines and biologic products in times of national and global emergencies and for unmet needs. The BMC facility, once certified as Good Manufacturing Practices (GMP) compliant, will have end-to-end production capability for mammalian cell-based biologics. This includes a production capacity of approximately 4000 liters per month, upstream and downstream processing, a quality control lab, and fill and finish. In the short-term, the BMC’s top priority and focus is to help secure the production of a COVID-19 vaccine for Canadians as quickly as possible, once one is approved by Health Canada. In the longer term, the BMC’s focus will be on providing innovative solutions for the domestic production and supply of novel biologics for the future, while providing Canada with access to a facility that is ready to respond to emergencies, such as a pandemic. 

Come and take part in the establishment of the facility and participate in the delivery of a GMP licensed vaccine manufacturing facility for Canada. NRC's intention is to transition the site to a different governance model over the next few years so the status of positions will be re-evaluated regularly.
For more information, visit  Biologics Manufacturing Centre - National Research Council Canada

The Manufacturing Supervisor is responsible for GMP manufacturing unit operations and overall product quality.  In the context of the new Biologics Manufacturing Centre, the team lead will be responsible for the hiring and training of a production team, and for writing and establishing processes and procedures.   The incumbent will lead the team to support equipment qualification and scheduling of equipment and personnel for manufacturing.

Key responsibilities include but are not limited to:
•    Supervise and plan upstream activities and procedures
•    Manage employee performance, ensure training plans are executed and updated
•    Support investigation process
•    Participate in gulatory inpection as subjet matter expert

Screening Criteria

Applicants must demonstrate within the content of their application that they meet the following screening criteria in order to be given further consideration as candidates:


Bachelor’s degree in Science, Engineering or related discipline.

Master degree in Science, Engineering or related discipline is an asset.


For information on certificates and diplomas issued abroad, please see Degree equivalency


  • Significant experience in supervising pharmaceutical or biopharmarceutical manufacturing operations, preference would be given to upstream processing (e.g. cell scale-up, bioreactors, clarification).
  • Experience working with single-use technology.
  • Experience leading and managing human resources.
  • Experience planning and scheduling of both physical and human resources.

Condition of Employment

Secret (II)

Language Requirements

Assessment Criteria

Candidates will be assessed on the basis of the following criteria:

Technical Competencies

  • Excellent understanding and knowledge of bioprocessing. 
  • Solid knowledge of GMP requirements as applied to pharmaceutical or biopharmaceutical products. 
  • Ability to create, review and revise SOPs, work instructions, test methods and processes.
  • Ability to communicate effectively both orally and in writing.

Behavioural Competencies

  • Management services - Conceptual and analytical ability (Level 3)
  • Management services - Communication (Level 3)
  • Management services - Results orientation (Level 3)
  • Management services - Teamwork (Level 3)
  • Management services - Self-knowing and self-development (Level 3)

Competency Profile(s)

For this position, the NRC will evaluate candidates using the following competency profile: Management Services


View all competency profiles



Relocation assistance will be determined in accordance with the NRC's directives.


This position is classified as a Research Council Officer (RCO), a group that is unique to the NRC. The RCO group uses a person-based classification system instead of the more common duties-based classification system. Candidates are remunerated based on their expertise, skill, outcomes and impacts of their previous work experience. The salary scale for this group is vast, from $56,374 to $159,364 per annum, which permits for employees of all levels from new graduates to world renowned experts to be fairly compensated for their contributions. 

In addition, the incumbent will receive the Bilingualism Bonus of $800 per year.


NRC employees enjoy a wide-range of competitive benefits including comprehensive health and dental plans, pension and insurance plans, vacation and other leave entitlements.


  • A pre-qualified list may be established for similar positions for a one year period.
  • NRC employees enjoy a wide-range of benefits including comprehensive health and dental plans, pension and insurance plans, vacation and other leave entitlements.
  • Preference will be given to Canadian Citizens and Permanent Residents of Canada. Please include citizenship information in your application.
  • The incumbent must adhere to safe workplace practices at all times.
  • We thank all those who apply, however only those selected for further consideration will be contacted.



Please direct your questions, with the requisition number (18024) to:


Telephone: 343-548-5849 

Closing Date: 29 September 2022 - 23h59 Eastern Time



For more information on career tools and other resources, check out Career tools and resources


*If you are currently a term or continuing employee at NRC, please apply through the SuccessFactors Careers module from your NRC computer.


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